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CAS 96-48-0 Pharmaceutical Intermediates 100% Safe GBL Gamma Butyrolactone

Categories Pharmaceutical Intermediates
Brand Name: YIHAN
Model Number: 96-48-0
Certification: GMP,USP,BP,ISO 9001
Place of Origin: China
Price: USD80 +L
Payment Terms: MoneyGram,Paypal, T/T, Western Union
Supply Ability: 5000kg/Month
Delivery Time: 3-5 work days
Packaging Details: Discreet Package or as Required.
Product Name: gbl
Suitable for: Adult
CAS: 96-48-0
Type: Pharmaceutical Intermediate
Appearance: Liquid Colorless
Purity: 99%
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    CAS 96-48-0 Pharmaceutical Intermediates 100% Safe GBL Gamma Butyrolactone

    1. Basic Info

    Product Name:Gamma-butyrolactone(GBL)
    Product Categories:organic interme-;Pharmaceutical Intermediates;-;Heterocycles;Miscellaneous Reagents;Halogenated Heterocycles ,Thiophenes ,Thiazolines/Thiazolidines
    Mol File:96-48-0.mol
    Gamma-butyrolactone(GBL) Structure

    2. Descriptions:

    amma-Butyrolactone (γ-butyrolactone or GBL) is a hygroscopic colorless liquid with a weak characteristic odor which is soluble in water. GBL is a common solvent and reagent in chemistry as well as being used as a flavouring, as a cleaning solvent, as a superglue remover, and as a solvent in some wet aluminium electrolytic capacitors. In humans it acts as a prodrug for GHB, and it is used as a recreational intoxicant with effects similar to alcohol.
    GBL has been found in extracts from samples of unadulterated wines. This finding indicates that GBL is a naturally occurring component in some wines and may be present in similar products. The concentration detected was approximately 5 μg/mL and was easily observed using a simple extraction technique followed by GC/MS analysis. GBL can be found in cheese flavourings but typically results in a content of 0.0002% GBL in the final foodstuff.
    GBL is a lactone. It is hydrolyzed under basic conditions, for example in a sodium hydroxide solution into sodium gamma-hydroxybutyrate, the sodium salt of gamma-hydroxybutyric acid. Under acidic conditions it forms an equilibrium mixture of both compounds. These compounds then may go on to form a polymer. When treated with a non-nucleophilic base, like lithium diisopropylamide, GBL can become an alpha-carbon nucleophile. The related compound caprolactone can be used to make a polyester in this manner.
    GBL is not active in its own right; its mechanism of action stems from its identity as a prodrug of GHB. The hypnotic effect of GHB is enhanced by combination with alcohol. A 2003 rat study showed that GBL in combination with ethanol showed a potentiated hypnotic effect, as the sleep-timing measure was longer than both of the individual components combined.

    3. Applications:

    GBL is an important chemical raw material and intermediate for medicine, and also the intermediate of the synthesize N-methyl pyrrolidone, α -pyrrolidone, polyvinyl pyrrolidone, α -acetyl-γ -butyrolactone, methionine and the butyric acid compounds. This product features a strong solubility, and is a good solvent for polyacrylonitrile, epoxy resin, polyvinyl butyral, polyvinyl chloride and its copolymers, and cellulose polymers. In medical industry, it is mainly used in synthesizing cyclopropylamine, etc.


    Check Item
    Standard ValueResults
    AppearanceTransparent liquidTransparent liquid
    Purity (wt%,GC)≥99.8099.92%
    Moisture (wt%,K.F.)≤0.030.02
    Color (Hazen)≤205
    Density (D,g/ml)1.125~1.1301.126
    Glycol (wt%,GC)≤0.020.003
    Tetrahydrofuran (wt%,GC)≤0.030.024

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    About us:

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